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The operation of drilling a tubular Neighborhood of a Knot 
 in 
 and then gluing in a solid
Torus so that its meridian curve goes to a 
-curve on the Torus boundary of the Knot exterior. 
Every compact connected 3-Manifold comes from Dehn surgery on a Link in 
.
See also Kirby Calculus
References
Adams, C. C.  The Knot Book: An Elementary Introduction to the Mathematical Theory of Knots.  New York: 
  W. H. Freeman, p. 260, 1994.